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Gamcemetinib (CC-99677) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway. It exhibits an IC50 of 156.3 nM in biochemical assays and an EC50 of 89 nM in cell-based assays.
Potent, covalent, and irreversible MK2 inhibitor
Exhibits IC50 of 156.3 nM in biochemical assays and EC50 of 89 nM in cell-based assays
Extracted from patent WO2020236636, compound 1
Available in solid and solution forms
Appearance: Solid, light yellow to yellow color
Useful for research purposes
Offers high purity of 99.1%
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Didecylamine (N-Decyldecan-1-amine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF) FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF) FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]
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PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560) Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR)
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This branched polyethylene glycol (PEG) linker contains a terminal amine and two azide (N3) functional groups and is supplied for research use. It is designed for use in bioconjugation workflows, including the synthesis of antibody-drug conjugates (ADCs).
Branched PEG linker with terminal amine and azide functionalities.
Suitable for antibody-drug conjugate synthesis and other bioconjugations.
High purity of 98.0%.
Molecular weight 750.84 g/mol.
Appearance: yellow to brown oil.
Storage: pure form -20°C for 3 years; 4°C for 2 years.
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Bis(2-chloroethyl)amine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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Diethylamine nonoate (diethylammonium salt) is a nitric oxide (NO) donor used in biochemical and pharmacological research. It is a crystalline solid (CAS 372965-00-9) with reported purity of 98.0% and molecular weight 206.29, typically stored at low temperatures to preserve activity.
Releases nitric oxide under physiological conditions.
High reported purity for reproducible experimental results.
Solid formulation suitable for accurate weighing and dosing.
Applicable to studies of vasodilation, cell signaling, and nitrosative stress.
Stable when stored at recommended low temperatures.
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